Endocrine Abstracts

IntroductionHomeostasis model assessment for insulin resistance (HOMA-IR) is widely used as a marker of insulin resistance. However, it reminds an expensive maker requiring insulin dosage. Several studies tried to found simple alternative predictors of insulin resistance such as triglycerides to HDL-C ratio with conflicting reported findings. The aim of our study was to investigate the usefulness of the atherogenic index of plasma (AIP) and the visceral ...

IntroductionThyroid hemiagenesis is defined as the absence of one lobe of the thyroid gland. It represents a rare congenital abnormality with a prevalence of 0.05 to 0.2%. The left lobe is more commonly affected than the right lobe. Thyroid hemiagenesis is incidentally found during a routine thyroid screen. Herein, we report a thyroid hemiagenesis revealed by a compensatory hypertrophy of the contralateral thyroid lobe in an adolescent girl with euthyroi...

Introduction: Congenital combined pituitary hormone deficiency (CCPHD) is a rare disorder characterized by an impaired production of two or more hormones of the anterior pituitary gland. It is linked to different genetic mutations and requires an early diagnosis to prevent burdensome developmental consequences. Primary ovarian insufficiency, disparately is the depletion of ovarian function with loss of functional primordial follicles before the age of 40 years due to multiple ...

Introduction: Thyroid hormones have an impact on the function and structure of the cardiac muscle.Aim: Investigate the prevalence and risk factors of structural and functional cardiac complications in patients with hyperthyroidism.Methods: We conducted a cross-sectional study on 30 patients with uncontrolled hyperthyroidism. Clinical, biological and therapeutic data were collected. A trans-thoracic echocardiography (TTE) and lung u...

Long fasting in patients with adrenal insufficiency could cause hypotension, dehydration or hypoglycaemia. No studies evaluated these risks and there is no recommendations about fasting for these patients. The aim of our study was to evaluate the potential risks of fasting during the month of Ramadan in patients with adrenal insufficiency.Subjects and methods: It is a cross sectional study that concerned 125 subjects (97 women and 28 men, mean age=47.8 y...

IntroductionPrimary hyperaldosteronism (PHA) is an increasingly prevalent cause of endocrine hypertension. It is characterized by unregulated aldosterone secretion with an excessive activation of mineralocorticoid receptors, inducing volume expansion, hypokalemia, endothelial dysfunction and fibrotic processes in the renal and cardiovascular systems. The aim of this study was to assess the metabolic, renal, and cardiovascular status in patients with prim...

IntroductionPrimary hyperaldosteronism (PHA) represents the most common cause of secondary hypertension. It is associated with a high risk of cardiovascular diseases (CVD), suggesting that aldosterone is implicated in the development of early atherosclerosis. Clinical studies have shown that atherogenic index of plasma (AIP) predicts cardiovascular risk. The aim of this study was to assess the associations between atherogenic index of plasma and cardiova...

IntroductionCurrent standard treatment of primary hypoparathyroidism is based on calcium and activated vitamin D supplementation. Iatrogenic severe hypercalcemia due to vitamin D intoxication is an uncommon complication rarely described in literature. Herein we report 5 cases of severe hypercalcemia secondary to vitamin D intoxication.ObservationsThree men and two women with chronic hypoparathyroidism were in...

IntroductionHyponatremia secondary to the syndrome of inappropriate anti diuretic hormone (SIADH) secretion is one of the most frequently observed electrolyte abnormalities in coronavirus disease -2019 (COVID-19). Herein, we report a new case of SIADH in a type 2 diabetic patient with COVID-19 pneumonia.ObservationA 79-year-old man with type 2 diabetes mellitus was admitted for a poor general condition. On ph...

IntroductionAcromegaly is an endocrine disorder resulting from an excess of growth hormone (GH). The cause is almost always a pituitary adenoma, and it affects through the insulin-like Growth Factor 1 (IGF-1) the cellular proliferation, increasing therefore the risk of malignancy. Herein, we describe a case of coexistence of papillary thyroid carcinoma and primary hyperparathyroidism in a patient with acromegaly.Case report<p c...